A complete set of canonical nucleobases in the carbonaceous asteroid (162173) RyuguOPEN ACCESS 

Toshiki Koga, Yasuhiro Oba, Yoshinori Takano, Hiroshi Naraoka, Nanako O. Ogawa, Kazunori Sasaki, Hajime Sato, Toshihiro Yoshimura & Naohiko Ohkouchi

Nature Astronomy, Published: 16 March 2026

LINK (OPEN ACCESS)
PDF (OPEN ACCESS)

“Organic molecules delivered from extraterrestrial materials may have played a key role in supplying building blocks for life on Earth. Here we report all five canonical nucleobases—purines (adenine and guanine) and pyrimidines (cytosine, thymine and uracil)—in samples returned from the C-type asteroid (162173) Ryugu by JAXA’s Hayabusa2 mission and compare the results with data from similar extraterrestrial material. Ryugu samples contain nearly equal amounts of purines and pyrimidines, whereas Murchison is enriched in purines and Bennu and Orgueil in pyrimidines. Samples from Ryugu, Bennu and Orgueil, which have a similar mineralogy and elemental composition, show purine-to-pyrimidine ratios negatively correlating with ammonia. These observations indicate that the nucleobases in these samples may have formed via a shared pathway depending on the physicochemical environment of the respective parent bodies. The detection of diverse nucleobases in asteroid and meteorite materials demonstrates their widespread presence throughout the Solar System and reinforces the hypothesis that carbonaceous asteroids contributed to the prebiotic chemical inventory of early Earth.”